New to Japan? Don’t Be Surprised by Tylenol’s Lighter Dose
Are you surprised to find that Tylenol or other acetaminophen-based medications in Japan contain less active ingredient than what you’re used to? If you’re feeling unwell and looking for a pain reliever or fever reducer, it’s important to understand how Japan’s over-the-counter (OTC) medication rules differ from those in other countries. This article explains the key differences and what you can expect when purchasing acetaminophen in Japan.
Contents
What Is Acetaminophen and How Is It Used?

Acetaminophen, also known as paracetamol in some countries, is one of the most commonly used medications worldwide to relieve pain and reduce fever. It’s widely considered a safe option for people of all ages when used correctly. Tylenol is the most well-known brand, but the active ingredient—acetaminophen—is also found in many generic products.
In countries like the United States, the United Kingdom, and many parts of Europe and Asia, a standard single dose of acetaminophen typically contains 500 mg per tablet. However, this is not the case in Japan.
Why Is the Dose Lower in Japan?

In Japan, government regulations currently allow over-the-counter medications to contain a maximum of 300 mg of acetaminophen per tablet. This dosage limit is designed with consideration for the general physique and metabolism of the Japanese population, as well as to ensure a higher safety margin in self-medication.
While this may seem inconvenient for those accustomed to stronger doses, Japanese health authorities prioritize safety and careful self-treatment when it comes to OTC medicine. For stronger or higher-dose formulations, a doctor’s prescription is required.
What Should Foreign Visitors Know?
If you’re visiting Japan and you’re used to taking 500 mg of acetaminophen in one dose, it may feel like the local options aren’t as effective. However, this doesn’t mean you won’t find relief—just that you may need to adjust your dosage schedule based on local products. Always follow the instructions on the package, and never exceed the maximum daily dose recommended.
Tylenol in Japan usually comes in 300 mg tablets, and other brands like Eve or Bufferin may also include acetaminophen as one of their active ingredients. Be careful not to double-dose if you’re using multiple medications for cold or flu relief.
Product


Tylenol Tablets
[Indications]
Relieves pain and reduces fever associated with headache, toothache, menstrual pain, joint pain, neuralgia, and sore throat.
[Dosage and Administration]
For adults (15 years and older): Take 1 tablet at a time, up to 3 times per day. Leave at least 4 hours between doses.
[Ingredients (per tablet)]
Acetaminophen 300 mg
Summary
While acetaminophen is a globally trusted medicine, the dosage limits in Japan are lower than in many other countries. This difference can be surprising to visitors, but it reflects Japan’s focus on safety in self-medication. If you’re unsure about what to take or need help choosing the right product, BLEZ Pharmacy is here to assist you. Our pharmacists can help you understand your options and ensure you find a safe and effective solution for your symptoms.