Introduction of a Japanese Laxative: Sullulac

Hello everyone! We are BLEZ Pharmacy, located in Nishiasakusa, Taito-ku, Tokyo. Today, we would like to introduce a commonly used laxative in Japan—Sullulac S.

Sullulac S is a stimulant laxative specifically designed for stubborn constipation. Its unique dual-active ingredient formula effectively alleviates severe constipation. The two active ingredients in the medication work through different mechanisms to help restore normal intestinal motility:

  • Bisacodyl: Acts on the upper part of the colon, stimulating the intestinal walls to promote peristalsis, which helps move stools along.
  • Sennoside Calcium: Activated by bacteria in the intestines, it further stimulates intestinal peristalsis, enhancing the laxative effect.

This dual-action mechanism comprehensively helps restore the natural peristalsis of the intestines, making it suitable for relieving temporary constipation, typically effective within 6 to 12 hours after ingestion. It is recommended to take it before bed for smooth bowel movements the following day.


When taking it, please pay attention to your body’s reactions and adjust the dosage as needed. Overuse may cause side effects such as abdominal pain or diarrhea; therefore, it is recommended to use it under the guidance of a physician or pharmacist. Feel free to consult the pharmacists at BLEZ Pharmacy for any related medical questions.

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